Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → 4-Carbobenzoxyoxybenzoic acid 1-methylpropyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | (+)-2-Butanol | HCID 444683 | — |
| 반응물 | 4-Carbobenzoxyoxybenzoyl chloride | HCID 19734054 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-Carbobenzoxyoxybenzoic acid 1-methylpropyl ester | HCID 54239335 | 18% |
반응 단계
A THF solution of 0.1 mole of (S)-(+)-2-butanol and 0.1 mole of triethylamine was stirred at 0° C., and a THF solution of 0.12 mole of 4-carbobenzoxyoxybenzoic acid chloride was added dropwise. The temperature was returned to the room temperature slowly, and stirring was carried out for 8 hours. After the reaction, the reaction solution was ether extracted, dried, concentrated, and purified by column chromatography, to obtain 5.7 g of 4-carbobenzoxyoxybenzoic acid 1-methylpropyl ester. (yield: 18%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04844835 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-86097eb86030476ead30188bc7baee4f |
| 출처 메모 | uspto-grants-1989_07 |