Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Bromide → 4-Keto-1-[(phenylmethoxy)carbonyl]-L-proline benzyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | N-Carbobenzyloxy-4-keto-L-proline | HCID 11076282 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-Keto-1-[(phenylmethoxy)carbonyl]-L-proline benzyl ester | HCID 11624525 | 49% |
반응 단계
5 g (0.02 mmol) of 4-keto-1-[(phenylmethoxy)carbonyl]-L-proline was dissolved in 50 ml dimethylformamide, 2.62 ml (0.022 mmol) of benzyl bromide and 3.59 g (0.026 mmol) of potassium carbonate were added. The reaction mixture was stirred for 1 hour followed by normal extractive work to give the title compound, 3.5 gm (49% yield), m.p. 55°-56° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04851514 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-9cce77e619164a6cbd81520207977231 |
| 출처 메모 | uspto-grants-1989_07 |