Cyclohexanecarboxaldehyde → HCID 59390144, 화합물

HRID 2358504

반응식

HRID 2358504 반응식
[C:1]1([P:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:8][CH2:9][NH2:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:17]1([CH:23]=O)[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>C(O)C>[CH:17]1([CH:23]=[N:10][CH2:9][CH2:8][P:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

참가 물질

4

반응물 2

HCID 16275CyclohexanecarboxaldehydeHCID 273264(2-Aminoethyl)diphenylphosphine

생성물 1

HCID 59390144HCID 59390144, 화합물수율 98%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Under argon, a solution of 2-diphenylphosphino-ethylamine (619.0 mg, 2.7 mmol) and cyclohexane carbaldehyde (306.2 mg, 2.73 mmol) in ethanol (15 mL) was heated at 65° C. (oil bath) for 4 h. Then, the solvent was removed in-vacuo to give the desired product (>98% by 1H-NMR) as a colourless liquid (880.5 mg, 2.7 mmmol, quantitative).

후처리

  1. customThen, the solvent was removed in-vacuo

출처 및 근거

ORD 기록
ord-c36fa6351f304f1dbf6713d72fad36a7
출처 데이터셋
uspto-grants-2010_07
특허 번호
US07763758B2

연결된 노트

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