Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aniline → Di[ethyl(diisopropyl)ammonium] 3-(3-sulfonatopropylanilino)-1-propanesulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | Propane sultone | HCID 14264 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | Di[ethyl(diisopropyl)ammonium] 3-(3-sulfonatopropylanilino)-1-propanesulfonate | HCID 86646640 | 94% |
반응 단계
A mixture of aniline (7 mmol), N,N-diisopropylethylamine (DIPEA, 18 mmol) and propane sultone (16 mmol) was heated in a pressure tube in 10 mL of acetonitrile at 120-130° C. for 9 h under argon atmosphere. The solvent was evaporated and ethylacetate was added. The precipitated DIPEA bromide was filtered off and the filtrate was evaporated. The residue was treated with ether to give di[ethyl(diisopropyl)ammonium] 3-(3-sulfonatopropylanilino)-1-propanesulfonate as a white or pinky-white solid. Yield: 94%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08642014B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-ea36cede2a55439582f41fdf9e0414d9 |
| 출처 메모 | uspto-grants-2014_02 |