Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,5-Dimethylisoxazole-4-carboxylic acid → 3,5-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-4-isoxazolecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,5-Dimethylisoxazole-4-carboxylic acid | HCID 75636 | — |
| 반응물 | 3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline | HCID 49852105 | — |
| 생성물 | 3,5-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-4-isoxazolecarboxamide | HCID 68427156 | 56% |
반응 단계
The title compound was prepared in 56% yield according to the general procedure for the preparation of the amides (Method C) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 3,5-dimethyl-4-isoxazolecarboxylic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07459456B2 |
| 출처 데이터셋 | uspto-grants-2008_12 |
| ORD ID | ord-457bef5c9b2c45568a878f79509ab56b |
| 출처 메모 | uspto-grants-2008_12 |