Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Delta-Valerolactone → HCID 12365950, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Delta-Valerolactone | HCID 10953 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | Benzamide, 5-chloro-N,2-dihydroxy- | HCID 169935 | — |
| 반응물 | 4-Chloropentanoyl chloride | HCID 12603962 | — |
| 촉매 | Zincchloride | HCID 3007855 | — |
| 생성물 | HCID 12365950 | HCID 12365950 | — |
반응 단계
A mixture of 30 g. of γ -valerolactone, 30 ml. of distilled thionyl chloride and 0.5 g. of zinc chloride was heated on a steam bath overnight and then distilled at 15 mm. The distillate was redistilled at 69- 70° and 15 mm. giving 34 g. of 4-chlorovaleryl chloride. The acid chloride was reduced catalytically, reacted with 5-chlorosalicylhydroxamic acid and the resulting intermediate was ring-closed according to the method described in Example 3. The product after recrystallization from trichloroethylene weighed 8.5 g. and melted at 210- 213° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04024139 |
| 출처 데이터셋 | uspto-grants-1977_05 |
| ORD ID | ord-c9f79d7b0bf3447899fe351abbbcff38 |
| 출처 메모 | uspto-grants-1977_05 |