3,4-Dichloro-N-methylaniline → HCID 57444242, 화합물

HRID 2401063

반응식

HRID 2401063 반응식
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]([NH:15][S:16]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[C:25]([F:28])([F:27])[F:26])(=[O:18])=[O:17])=[N:11][CH:12]=[CH:13][N:14]=2)=[CH:5][CH:4]=1.[Cl:29][C:30]1[CH:31]=[C:32]([CH:35]=[CH:36][C:37]=1[Cl:38])[NH:33][CH3:34]>>[Cl:29][C:30]1[CH:31]=[C:32]([N:33]([CH2:2][C:3]2[CH:8]=[CH:7][C:6]([C:9]3[C:10]([NH:15][S:16]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=4[C:25]([F:27])([F:26])[F:28])(=[O:17])=[O:18])=[N:11][CH:12]=[CH:13][N:14]=3)=[CH:5][CH:4]=2)[CH3:34])[CH:35]=[CH:36][C:37]=1[Cl:38]

참가 물질

3

반응물 2

HCID 28009313,4-Dichloro-N-methylanilineHCID 57444250N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide2회

생성물 1

HCID 57444242HCID 57444242, 화합물수율 63%

실험 절차

Following the general method as outlined in Example 1 (Method B), starting from N-{3-[4-(chloromethyl)phenyl]pyrazin-2-yl}-2-(trifluoromethyl)benzenesulfonamide (Intermediate 9), and 3,4-dichloro-N-methylaniline, the title compound was isolated as a yellow solid in 63% yield (91% purity by HPLC).

출처 및 근거

ORD 기록
ord-3932349de9894e09bfb77e40a090d87d
출처 데이터셋
uspto-grants-2014_08
특허 번호
US08796280B2

연결된 노트

불러오는 중…