Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-tert-Butyl-1,3-thiazol-2-amine → N-(4-tert-butylthiazol-2-yl)-3-(3,4-difluorophenyl)-6,7-dihydropyrano[4,3-c]pyrazole-1(4H)-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-tert-Butyl-1,3-thiazol-2-amine | HCID 2734202 | — |
| 반응물 | (S)-3-(3,4-difluorophenyl)-N-(3,3-dimethyl-1-(methyl-amino)-1-oxobutan-2-yl)-6,7-dihydropyrano[4,3-c]pyrazole-1(4H)-carboxamide | HCID 46834697 | — |
| 생성물 | N-(4-tert-butylthiazol-2-yl)-3-(3,4-difluorophenyl)-6,7-dihydropyrano[4,3-c]pyrazole-1(4H)-carboxamide | HCID 46830659 | — |
반응 단계
Compound 56 was prepared according to the procedure described for the synthesis of compound 28 by replacing tert-leucine methylamide with 2-amino-4-tert-butylthiazole. LCMS (+ESI) m/z=419.2 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653127B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-5ae4b90e57fe4e0e8d17b3622fcd3b34 |
| 출처 메모 | uspto-grants-2014_02 |