Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyrimidine-4-carbohydrazide → N-pentyl-5-(3-pyrimidin-4-yl-1H-1,2,4-triazol-5-yl)-1H-imidazol-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyrimidine-4-carbohydrazide | HCID 468664 | — |
| 반응물 | methyl 4-(pentylamino)-1H-imidazole-5-carbimidothioate | HCID 135984704 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-pentyl-5-(3-pyrimidin-4-yl-1H-1,2,4-triazol-5-yl)-1H-imidazol-4-amine | HCID 135984710 | — |
반응 단계
The mixture of methyl 4-(pentylamino)-1H-imidazole-5-carbimidothioate (1.5 g, 6.6 mmol) and pyrimidine-4-carbohydrazide (1.2 g, 8.7 mmol) in ethanol (10 mL) was refluxed overnight. The reaction mixture was concentrated under reduced pressure to yield the desired product as light green viscous oil. LCMS calculated for C1-4H19N8 (M+H): 299.2. found: 299.1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07863285B2 |
| 출처 데이터셋 | uspto-grants-2011_01 |
| ORD ID | ord-2d34856a20d441a9a9d769ba5795218e |
| 출처 메모 | uspto-grants-2011_01 |