Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl isocyanate → 4-(tert-Butylureido)-N-{2-[4-(4-fluorobenzoyl)-piperidino]ethyl}-N-(2-methoxyphenyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl isocyanate | HCID 62412 | — |
| 반응물 | 4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(2-methoxyphenyl)benzamide | HCID 19690043 | — |
| 생성물 | 4-(tert-Butylureido)-N-{2-[4-(4-fluorobenzoyl)-piperidino]ethyl}-N-(2-methoxyphenyl)benzamide | HCID 19690014 | 77.6% |
반응 단계
Using 4-amino-N-{2-[4-(4-fluorobenzoyl)piperidino]ethyl}-N-(2-methoxyphenyl)benzamide (77.7 mg, 0.164 mmol) and tertbutyl isocyanate (0.022 ml, 0.196 mmol), the procedure of inventive Example 144 was repeated to obtain 72.9 mg (77.6%) of the title compound in a colorless oily form.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728835 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-13297e7c81bb418aa27b32cfac5bc697 |
| 출처 메모 | uspto-grants-1998_03 |