Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → [2-Chloro-4-fluoro-5-(3-trifluoromethyltriazolyl)phenyl] 2,2,2-trifluoroethyl sulfide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1,1,1-Trifluoro-2-iodoethane | HCID 67709 | — |
| 반응물 | 1,1'-Thiodi-[2-chloro-4-fluoro-5-(3-trifluoromethyltriazolyl)benzene] | HCID 22170914 | — |
| 반응물 | Sodium Formaldehyde Sulfoxylate | HCID 23689980 | — |
| 생성물 | [2-Chloro-4-fluoro-5-(3-trifluoromethyltriazolyl)phenyl] 2,2,2-trifluoroethyl sulfide | HCID 86587601 | 96.6% |
반응 단계
1.8 g (3.0 mmol) of 1,1′-thiodi-[2-chloro-4-fluoro-5-(3-trifluoromethyltriazolyl)benzene], 2.0 g (13.0 mmol) of Rongalite, 2.0 g (14.5 mmol) of potassium carbonate and 3.2 g (17.6 mmol) of 2,2,2-trifluoroethyl iodide were reacted in the same way as in Example 2 (3) and afforded 1.1 g of [2-chloro-4-fluoro-5-(3-trifluoromethyltriazolyl)phenyl] 2,2,2-trifluoroethyl sulfide (yield 47.8%) as white crystals (m.p. 56-58° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858639B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-8be04ddb476d488398190c4032a8b95d |
| 출처 메모 | uspto-grants-2005_02 |