Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium formate → tert-Butyl 5-amino-3-methyl-1H-indazole-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium formate | HCID 2723923 | — |
| 반응물 | tert-Butyl 3-methyl-5-nitro-1H-indazole-1-carboxylate | HCID 22567205 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | tert-Butyl 5-amino-3-methyl-1H-indazole-1-carboxylate | HCID 59276571 | 89% |
반응 단계
5-Amino-N-tert-butoxycarbonyl-3-methyl-1H-indazole can be obtained as described in Example 6 from 3.4 g of N-tert-butoxycarbonyl-3-methyl-5-nitro-1H-indazole, 50 ml of methanol, 0.61 g of 10% palladium-on-charcoal and 3.53 g of ammonium formate. 2.7 g of 5-amino-N-tert-butoxycarbonyl-3-methyl-1H-indazole are thus obtained in the form of a cream solid melting at 185° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858638B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-fcdd43b1809b47dfab16fdca94887db9 |
| 출처 메모 | uspto-grants-2005_02 |