Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylsilyl iodide → HCID 178434305, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylsilyl iodide | HCID 85247 | — |
| 반응물 | N-(N-tert-butoxycarbonyl-3-methyl-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide | HCID 22567145 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | HCID 178434305 | HCID 178434305 | 30.8% |
반응 단계
2-Methylsulfonyl-N-(3-methyl-1H-indazol-5-yl)benzenesulfonamide can be obtained as described in Example 6 from 1.45 g of N-(N-tert-butoxycarbonyl-3-methyl-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide, 12.6 ml of chloroform and 0.44 ml of iodotrimethylsilane. 0.35 g of 2-methylsulfonyl-N-(3-methyl-1H-indazol-5-yl)benzenesulfonamide is thus obtained in the form of a white solid melting above 260° C. (analysis: C15H15N3O4S2 % calculated C, 49.30; H, 4.14; N, 11.50; O, 17.51; S, 17.55. % found C, 48.99; H, 4.45; N, 11.67; S, 17.23).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858638B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-9300e756fe064eb89c3ca6fffc294d00 |
| 출처 메모 | uspto-grants-2005_02 |