Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzenesulfonyl chloride → N-(1H-indazol-5-yl)benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzenesulfonyl chloride | HCID 7369 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 1H-Indazol-5-amine | HCID 88012 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | N-(1H-indazol-5-yl)benzenesulfonamide | HCID 4142281 | 58.5% |
반응 단계
N-(1H-Indazol-5-yl)benzenesulfonamide can be obtained as described in Example 1 from 0.5 g of 5-amino-1H-indazole, 25 ml of tetrahydrofuran, 1.05 ml of triethylamine and 0.73 g of benzenesulfonyl chloride. 0.6 g of N-(1H-indazol-5-yl)benzenesulfonamide is thus obtained in the form of a cream solid melting at 179° C. (analysis C13H11N3O2S % calculated C, 57.13; H, 4.06; N, 15.37; O, 11.71; S, 11.73. % found C, 56.90; H, 4.24; N, 14.21; S, 10.67).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858638B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-05934cb3b031497c96bada5ab7dfd146 |
| 출처 메모 | uspto-grants-2005_02 |