Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 1,2:5,6-Bis-O-(1-methylethylidene)-alpha-D-allofuranose
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Diacetone-D-glucose | HCID 7067560 | — |
| 반응물 | DMSO acetic anhydride | HCID 86609981 | — |
| 생성물 | 1,2:5,6-Bis-O-(1-methylethylidene)-alpha-D-allofuranose | HCID 7157054 | — |
반응 단계
Sowa, W. and Thomas, G. H. S., (Can. J. of Chem., 1966, Vol. 44, 836-838) used the DMSO/acetic anhydride oxidation of 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose in small scale (10 mmole) using a 20 fold excess of acetic anhydride. The ulose was then reduced providing 1,2:5,6-di-O-isopropylidene-α-D-allofuranose of poor quality, thus the product had to be column purified. Overall this procedure is not suitable for large-scale productions due to the large reagent consumption, two step procedure and the column purification step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858726B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-a62ddce00f3040878d58f6747e85353c |
| 출처 메모 | uspto-grants-2005_02 |