참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 2-(4-Methoxyphenyl)indolizine | HCID 346949 | — |
| 생성물 | 2-(4-Methoxyphenyl)indolizine-3-carbaldehyde | HCID 3800656 | — |
반응 단계
A slurry of 20 g of 2-(4-methoxy phenyl) indolizine in 35 ml of DMF was added to a solution of 10 ml of phosphorus oxychloride in 30 ml of DMF at 10-20° C. After the reaction solution was stirred at 40° for 40 min., it was added to 200 g of ice. 120 g of 25 percent sodium hydroxide solution was added and the resulting mixture was heated to 55° C., cooled, and filtered. The air-dried product weighed 23 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04701398 |
|---|
| 출처 데이터셋 | uspto-grants-1987_10 |
|---|
| ORD ID | ord-0eef2b4bac6647ffa1de02d2a5220f89 |
|---|
| 출처 메모 | uspto-grants-1987_10 |
|---|
