Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Phenylethanethiol → 6-(5-Isopropyl-2-methoxyphenyl)-2,2-dimethyl-4-phenethylsulfanylmethyl-1,2-dihydroquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Phenylethanethiol | HCID 78126 | — |
| 반응물 | 5-Isopropyl-2-methoxyphenylboronic acid | HCID 4589190 | — |
| 반응물 | Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester | HCID 20760320 | — |
| 생성물 | 6-(5-Isopropyl-2-methoxyphenyl)-2,2-dimethyl-4-phenethylsulfanylmethyl-1,2-dihydroquinoline | HCID 10004290 | — |
반응 단계
Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester was coupled with 5-isopropyl-2-methoxyphenylboronic acid. Bromination and coupling reaction with 2-phenylethanethiol gave 30 mg of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06858627B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-4175792f7f1046e493a98b8019fb87d9 |
| 출처 메모 | uspto-grants-2005_02 |