Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzaldehyde → p-(2-(Dimethylamino)ethoxy)benzaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzaldehyde | HCID 126 | — |
| 반응물 | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | p-(2-(Dimethylamino)ethoxy)benzaldehyde | HCID 84823 | 46.6% |
반응 단계
The reaction between 61.0 g (0.50 mole) of 4-hydroxybenzaldehyde, 24.0 g of 50% NaH, and 341 ml of 2.2 N (0.75 mole) 2-dimethylaminoethyl chloride in toluene in a procedure described for Example 2,part A, gives 45.0 g (46%) of colorless product, bp 140°-142°/2 mm. Lit. bp 185°-187°/15 mm.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04038274 |
| 출처 데이터셋 | uspto-grants-1977_07 |
| ORD ID | ord-a2ddb5f051504bd5afee04ff26e57a22 |
| 출처 메모 | uspto-grants-1977_07 |