Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(Diisopropylamino)ethyl chloride → alpha-[2-(Diisopropylamino)ethyl]-alpha-(2-piperidinoethyl)-alpha-(2-pyridyl)acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(Diisopropylamino)ethyl chloride | HCID 7312 | — |
| 반응물 | 1-(2-Chloroethyl)piperidine | HCID 74827 | — |
| 반응물 | 4-Diisopropylamino-2-phenyl-butyronitrile | HCID 12612210 | — |
| 반응물 | 4-Diisopropylamino 2-(2-pyridyl)butyronitrile | HCID 13319674 | — |
| 생성물 | alpha-[2-(Diisopropylamino)ethyl]-alpha-(2-piperidinoethyl)-alpha-(2-pyridyl)acetonitrile | HCID 21320527 | — |
반응 단계
Substitution of equivalent quantities of α-[2-(diisopropylamino)ethyl]-α-(2-pyridyl)acetonitrile and 1-(2-chloroethyl)piperidine for α-[2-(diisopropylamino)ethyl]-α-phenylacetonitrile and 2-chloro-N,N-diisopropylethylamine called for respectively in the procedure of Example 2, Method B affords α-[2-(diisopropylamino)ethyl]-α-(2-piperidinoethyl)-α-(2-pyridyl)acetonitrile, as an oil boiling at about 160°-170° C. at 0.5-0.7 mm. pressure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04153797 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-032e891ed1cb4200a7a8e53af8d9f620 |
| 출처 메모 | uspto-grants-1979_05 |