Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidin-4-ol → HCID 178501992, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidin-4-ol | HCID 79341 | — |
| 반응물 | HCID 178501976 | HCID 178501976 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 178501992 | HCID 178501992 | — |
반응 단계
A suspension of 2.5 g. of dimethyl 6-chloro-2,4-pyrimidine-dicarbamate-3-oxide in 100 ml. of methylene chloride is treated with 10 g. of 4-hydroxy-piperidine and stirred at room temperature under an argon atmosphere for 70 hours. The separated precipitate is filtered off and recrystallized from a mixture of methylene chloride and methanol, there being obtained pure dimethyl racemic-6-(4-hydroxy-1-piperidinyl)-2,4-pyrimidine-dicarbamate-3-oxide, having a melting point of 265°-266° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04150131 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-a6bfb469abe94c7fb7557defc99746cb |
| 출처 메모 | uspto-grants-1979_04 |