Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Nafimidone monohydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)ethanone | HCID 51200 | — |
| 생성물 | Nafimidone monohydrochloride | HCID 51199 | — |
반응 단계
Ethereal hydrogen chloride is added dropwise to a solution of 1.0 g. 1-(2-naphthoylmethyl)imidazole in 100 ml. anhydrous benzene until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized from methanol/acetone to yield 1-(2-naphthoylmethyl)imidazole hydrochloride, m.p. 226°-228.5° C. (decomp.)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04150153 |
| 출처 데이터셋 | uspto-grants-1979_04 |
| ORD ID | ord-6ba27d46b2f5423ca8e9dc5ac6a8baa3 |
| 출처 메모 | uspto-grants-1979_04 |