Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzo(d)thiazol-2-amine → 5-(Imidazo[2,1-b]benzothiazol-2-yl)-3-nitropyrocatechol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzo(d)thiazol-2-amine | HCID 8706 | — |
| 반응물 | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-(Imidazo[2,1-b]benzothiazol-2-yl)-3-nitropyrocatechol | HCID 21459069 | — |
반응 단계
A mixture of 1.95 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone, 1.06 g of 2-aminobenzothiazole and 50 ml of ethanol is heated to boiling under reflux for 17 hours. The reaction mixture is then cooled to room temperature, whereupon the crystals are removed by filtration under suction. There is obtained 5-(imidazo[2,1-b]benzothiazol-2-yl)-3-nitropyrocatechol of m.p. 303°-305° (from N,N-dimethylformamide/methanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05389653 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-c6b1a535c5ee4613b184f2f0f99a485a |
| 출처 메모 | uspto-grants-1995_02 |