Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Leucinol → HCID 178428753, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Leucinol | HCID 111307 | — |
| 반응물 | 2-Methyl-4-nitrophenyl isothiocyanate | HCID 145621 | — |
| 생성물 | HCID 178428753 | HCID 178428753 | — |
반응 단계
(1S)-1-(Hydroxymethyl)-3-methylbutylamine was converted to (1S)-1-(chloromethyl)-3-methylbutanammonium chloride as described in Method B7a. 2-Methyl-4-nitrophenyl isothiocyanate was reacted with (1S)-1-(chloromethyl)-3-methylbutanammonium chloride according to Method C1a to give (4S)-2-(2-methyl-4-nitrophenylimino)-4-isobutyl-1,3-thiazolidine. The thiazolidine was reacted with methyl iodide according to Method D2a to afford (4S)-2-(2-methyl-4-nitrophenylimino)-4-isobutyl-3-methyl-1,3-thiazolidine HCl salt.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353006B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-9d0636127e9d4c7092550463f76dc4bc |
| 출처 메모 | uspto-grants-2002_03 |