Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → Benzo[b]thiophene-2-sulfonic acid [1-(4-amino-3-cyanobenzyl)-2-oxo-pyrrolidin-3-(S)-yl]amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | 1-Benzothiophene-2-sulfonyl chloride | HCID 2776333 | — |
| 반응물 | 4-amino-3-(3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)benzonitrile dihydrochloride | HCID 22883631 | — |
| 생성물 | Benzo[b]thiophene-2-sulfonic acid [1-(4-amino-3-cyanobenzyl)-2-oxo-pyrrolidin-3-(S)-yl]amide | HCID 53897651 | — |
반응 단계
The title compound (0.131 g, 0.307 mmol) is prepared as in EXAMPLE 1, Part E from 4-amino-3-(3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)benzonitrile dihydrochloride (0.135 g, 0.445 mmol) and benzo[b]thiophene-2-sulfonyl chloride (0.114 g, 0.49 mmol) in acetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731315 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-2304608b9689445eb80f2a17289a2a83 |
| 출처 메모 | uspto-grants-1998_03 |