Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylglyoxal → N-(3-(4-Methylphenyl)-1,1-dimethylpropyl)-2-hydroxy-2-phenyl ethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylglyoxal | HCID 14090 | — |
| 반응물 | 3-(Trifluoromethyl)phenylglyoxal | HCID 2783284 | — |
| 반응물 | 2-Methyl-4-(4-methylphenyl)butan-2-amine | HCID 23322167 | — |
| 생성물 | N-(3-(4-Methylphenyl)-1,1-dimethylpropyl)-2-hydroxy-2-phenyl ethanamine | HCID 23322158 | — |
반응 단계
The title compound was prepared in the manner described in Example 9, replacing 2-(4-methylphenyl)-1,1-dimethylethanamine by 3-(4-methylphenyl)-1,1-dimethylpropanamine and 3-trifluoromethylphenyl glyoxal by phenylglyoxal. The chromatographed material was recrystallised from hexane to give the title compound m.p. 107-110. τ (CDCl3) 8.95 (6H, s), 8.2-8.7 (2H, m), 7.8 (3H, s), 7.3-7.7 (4H, m), 5.7-6.5 (2H, m), 5.5 (1H, t, J=6 Hz), 2.9 (4H, s), 2.7 (4H, m).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04588749 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-250f6c9aa124474789d01ccb26ee94bd |
| 출처 메모 | uspto-grants-1986_05 |