Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol | HCID 9794153 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethene | HCID 18936291 | — |
반응 단계
1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol (900 mg) in dry chloroform was treated with 1M anhydrous hydrogen chloride in diethylether (1.1 equivalents). After 10 minutes at room temperature, aqueous sodium hydrogen carbonate was added and the mixture was extracted with dichloromethane. The material thus obtained was purified by flash chromatography to give the title compound as an almost colourless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731335 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-f8ae87d4cdb04743b3be2fcbfdc05511 |
| 출처 메모 | uspto-grants-1998_03 |