Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Anilino-3-nitrobenzoic acid → 3-Amino-4-phenylamino-benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Anilino-3-nitrobenzoic acid | HCID 3824366 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-Amino-4-phenylamino-benzoic acid | HCID 773821 | — |
반응 단계
A solution of the 4-anilino-3-nitrobenzoic acid (20.1 mmol) in THF (100 mL) was charged with 10% Pd/C (500 mg) and the reaction flask evacuated and subsequently charged with H2 (g) three times. The mixture was stirred vigorously for 12 h after which time it was filtered through diatomaceous earth and the filtrate concentrated in vacuo to give the desired 3-amino-4-anilinobenzoic acid: e.g. 3-amino4-[(3-hydroxyphenyl)amino]benzoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419995B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-0a653020fe1a4d3f9a6e01a5511e2f2e |
| 출처 메모 | uspto-grants-2008_09 |