Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phloroglucinol → 5,7-Dihydroxy-4-methylcoumarin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phloroglucinol | HCID 359 | — |
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | Sulfuric acid hydrate (1:1) | HCID 21910475 | — |
| 생성물 | 5,7-Dihydroxy-4-methylcoumarin | HCID 5354284 | — |
반응 단계
A mixture of 2.77 g (22 mmol) of phloroglucinol and 2.6 g (20 mmol) of ethyl acetoacetate were melted together, the mixture was cooled, and 40 ml of a mixture of sulfuric acid/water (75% w/w) was added rapidly to the semi-solid mass. The mixture was stirred for 24 h, during which time a semi-solid mass formed. It was poured into a mixture of ice/water (300 ml) containing 5 g of sodium acetate and the precipitate was recovered by suction filtration.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07420054B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-633683c5b109479a96268fd5d4c3e362 |
| 출처 메모 | uspto-grants-2008_09 |