Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → HCID 66886112, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 3-(3,5-Difluoro-phenyl)-5-methyl-[1,2,4]triazole | HCID 43166806 | — |
| 반응물 | tert-butyl N-(4-chloro-2-methylbutan-2-yl)carbamate | HCID 57429079 | — |
| 촉매 | Tetrabutylammonium Iodide | HCID 67553 | — |
| 용매 | 2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl- | HCID 81646 | — |
| 생성물 | HCID 66886112 | HCID 66886112 | — |
반응 단계
3.74 g (19 mmol) 3-(3,5-difluoro-phenyl)-5-methyl-[1,2,4]triazole in 25 mL DMPU are reacted with 0.92 g (23 mmol, 60%) sodium hydride, 6.37 g (29 mmol) tert-butyl (3-chloro-1,1-dimethyl-propyl)-carbamate and 1.27 g (3.5 mmol) tetrabutylammonium iodide analogously to intermediate product 1c). Oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423036B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-1798b943cf5c4f93a6535bbb920c5aa5 |
| 출처 메모 | uspto-grants-2008_09 |