Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Amino-1-Boc-piperidine → 4-[6-Amino-5-(2-fluoro-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Amino-1-Boc-piperidine | HCID 1268291 | — |
| 반응물 | (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone | HCID 58590830 | — |
| 생성물 | 4-[6-Amino-5-(2-fluoro-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid tert-butyl ester | HCID 58590837 | — |
반응 단계
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone (Example 7) and 4-amino-1-N-Boc-piperidine (Astatech, >96%) using the procedure described in Step B, Example 6. HRMS, observed: 415.2143, Calcd for (M+H)+: 415.2140.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423051B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-24b9ae238acc4a2d87ee58fb37f2cbeb |
| 출처 메모 | uspto-grants-2008_09 |