Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate → [2-Amino-6-(1-methanesulfonyl-piperidin4-ylamino)-pyridin-3-yl]-(2-fluoro-phenyl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | [1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate | HCID 11975076 | — |
| 반응물 | (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone | HCID 58590830 | — |
| 생성물 | [2-Amino-6-(1-methanesulfonyl-piperidin4-ylamino)-pyridin-3-yl]-(2-fluoro-phenyl)-methanone | HCID 11610846 | — |
반응 단계
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone (Example 7) and 1-methanesulfonyl-piperidin-4-ylamine (Step A, Example 6) using the procedure described in Step B. Example 6. HRMS, observed: 392.1329, calcd for M+: 392.1318.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423051B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-d4d179e4f6114701810dd15f310df06f |
| 출처 메모 | uspto-grants-2008_09 |