Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 4-amino-1-piperidinecarboxylate → 4-[6-Amino-5-(5-fluoro-2-methoxy-4-methyl-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 4-amino-1-piperidinecarboxylate | HCID 100867 | — |
| 반응물 | (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone | HCID 58590831 | — |
| 생성물 | 4-[6-Amino-5-(5-fluoro-2-methoxy-4-methyl-benzoyl)-pyridin-2-ylamino]-piperidine-1-carboxylic acid ethyl ester | HCID 11524792 | — |
반응 단계
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(5-fluoro-2-methoxy-4-methyl-phenyl)-methanone (Example 43) and ethyl-4-amino- 1-piperidine carboxylate (Aldrich 96%) using the procedure described in Step B. Example 6. HRMS, observed: 431.2090, Calcd for (M+H)+: 431.2089.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423051B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-06dfe7381dc5433d95e2da75f0c5647d |
| 출처 메모 | uspto-grants-2008_09 |