Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Chloro-2-fluoro-4-iodo-5-methoxybenzene → (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Chloro-2-fluoro-4-iodo-5-methoxybenzene | HCID 21070630 | — |
| 반응물 | 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide | HCID 58590824 | — |
| 생성물 | (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone | HCID 58590823 | — |
반응 단계
The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 5-chloro-4-fluoro-2-iodoanisole (prepared as described in Step A above) using the procedure described in Example 7. HRMS, observed: 312.9943, Calcd for (M−H)+: 312.9947.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423051B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-8b2ab23d421d4ca7b820de3c492a45e2 |
| 출처 메모 | uspto-grants-2008_09 |