Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → (3-Bromophenyl)acetaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | 3-Bromostyrene | HCID 74870 | — |
| 반응물 | HCID 178418268 | HCID 178418268 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (3-Bromophenyl)acetaldehyde | HCID 20387554 | — |
반응 단계
A mixture of lead tetraacetate (3.6 g, 8.2 mmol) and trifluoroacetic acid (8.25 mL) at 0° C. is treated dropwise with a solution of 1-bromo-3-vinylbenzene (1.5 g, 8.2 ml) in dichloromethane, allowed to warm to room temperature, stirred for 2 h at room temperature, diluted with dichloromethane, poured into water, stirred vigorously and filtered through a pad of celite. The filtrate is separated. The filtercake is rinsed with additional portions of dichloromethane. The combined organic phases are washed sequentially with water, NaHCO3 and brine, dried over MgSO4 and concentrated in vacuo to afford (3-bromophenyl)acetaldehyde.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423158B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-b7016977149e4bafa9e7f3429a8baa7d |
| 출처 메모 | uspto-grants-2008_09 |