4,6-Dichloropyrimidine → HCID 86586218, 화합물

HRID 31910

반응식

HRID 31910 반응식
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[CH:4][N:3]=1.[NH:9]1[CH:13]=[CH:12][N:11]=[C:10]1[C:14]1[C:15]([C:34]2[CH:39]=[CH:38][C:37]([C:40]#[N:41])=[CH:36][CH:35]=2)=[N:16][C:17]([NH:20][CH2:21][CH2:22][NH:23]C2C=CC(C(F)(F)F)=CN=2)=[N:18][CH:19]=1>>[Cl:8][C:6]1[N:5]=[CH:4][N:3]=[C:2]([NH:23][CH2:22][CH2:21][NH:20][C:17]2[N:16]=[C:15]([C:34]3[CH:39]=[CH:38][C:37]([C:40]#[N:41])=[CH:36][CH:35]=3)[C:14]([C:10]3[NH:9][CH:13]=[CH:12][N:11]=3)=[CH:19][N:18]=2)[CH:7]=1

참가 물질

3

반응물 2

HCID 709434,6-DichloropyrimidineHCID 571424814-{5-Imidazolyl-2-[(2-{[5-(trifluoromethyl) (2-pyridyl)]amino}ethyl)amino]pyrimidin-4-yl}benzenecarbonitrile

생성물 1

HCID 86586218HCID 86586218, 화합물

실험 절차

4-[2-({2-[(6-chloropyrimidin-4-yl)amino]ethyl}amino)-5-imidazolylpyrimidin-4-yl]benzenecarbonitrile was prepared from 4,6-dichloropyrimidine using the general method for 4-{5-imidazolyl-2-[(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amino]pyrimidin-4-yl}benzenecarbonitrile.

출처 및 근거

ORD 기록
ord-6b78c798a5a14f868c6e79fe1ff2db68
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425557B2

연결된 노트

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