Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Dichloroacetone → 4-Chloromethyl-2-(3-methyl-2-thienyl)oxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Dichloroacetone | HCID 10793 | — |
| 반응물 | 3-Methylthiophene-2-carboxamide | HCID 588128 | — |
| 생성물 | 4-Chloromethyl-2-(3-methyl-2-thienyl)oxazole | HCID 22009832 | 61% |
반응 단계
In substantially the same manner as in Reference Example 47, 3-methyl-2-thiophenecarboxamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(3-methyl-2-thienyl)oxazole. The yield was 61%. Recrystallization from ethyl acetate-hexane gave colorless needles, mp 95-96° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211215B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-6e3384b4939f4fcf97b097459e830109 |
| 출처 메모 | uspto-grants-2001_04 |