Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-[3-(4-Hydroxy-3-methoxyphenyl)propyl]-1,2,4-triazole → 1-[3-[3-methoxy-4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]-1,2,4-triazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-[3-(4-Hydroxy-3-methoxyphenyl)propyl]-1,2,4-triazole | HCID 22009715 | — |
| 반응물 | 4-Chloromethyl-2-styryl-oxazole | HCID 22009752 | — |
| 생성물 | 1-[3-[3-methoxy-4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]-1,2,4-triazole | HCID 22009670 | 62% |
반응 단계
In substantially the same manner as in Working Example 37, 1-[3-(4-hydroxy-3-methoxyphenyl)propyl]-1,2,4-triazole was allowed to react with 4-chloromethyl-2-[(E)-2-phenylethenyl]oxazole to give 1-[3-[3-methoxy-4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]-1,2,4-triazole. The yield was 62%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 113-114° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211215B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-f331cd630d6847788e012101965cc8b4 |
| 출처 메모 | uspto-grants-2001_04 |