Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloromethyl-2-(2-furyl)oxazole → 2-(2-Furyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloromethyl-2-(2-furyl)oxazole | HCID 22009706 | — |
| 반응물 | 1-[3-(4-Hydroxyphenyl)propyl]imidazole | HCID 22009818 | — |
| 생성물 | 2-(2-Furyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole | HCID 22009821 | 31% |
반응 단계
In substantially the same manner as in Working Example 109, 1-[3-(4-hydroxyphenyl)propyl]imidazole was allowed to react with 4-chloromethyl-2-(2-furyl)oxazole to give 2-(2-furyl)-4-[4-[3-(1-imidazolyl)propyl]phenoxymethyl]oxazole. The yield was 31%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 92-93° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211215B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-fdd8f8e2ef8d4e82af015f3fac9cc0f2 |
| 출처 메모 | uspto-grants-2001_04 |