Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Acetylbenzoic acid → 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Acetylbenzoic acid | HCID 68474 | — |
| 반응물 | 1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene | HCID 22007332 | — |
| 용매 | Ethylene Glycol | HCID 174 | — |
| 생성물 | 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene | HCID 22007441 | 87.5% |
반응 단계
1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene (177 mg), 1-carboxy-2-methylcarbonylbenzene (86 mg) and ethylene glycol (1 ml) are treated in the same manner as in Example 104-(3) to give 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene (211 mg), which is listed in Table 14.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06214996B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-2ef8657737a6492fac4ec11efdf6fe8d |
| 출처 메모 | uspto-grants-2001_04 |