Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Sulfide → HCID 22003635, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Sulfide | HCID 402 | — |
| 반응물 | 2-Ethyl-9,10-dihydro-7-methyl-4H-benzo[5,6]cyclohepta[1,2-d]oxazol-4-one | HCID 22003642 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 22003635 | HCID 22003635 | — |
반응 단계
Hydrogen sulphide was passed through a suspension of potassium tert-butoxide (9.31 g) in N,N-dimethylformamide (80 ml) at 5° C. until the mixture was saturated. The product from example 1 step (v) (5.0 g) was added and the reaction mixture stirred at room temperature for 2 h. The mixture was poured onto ice, acidified to pH3 and extracted with ethyl acetate. The organic phase was washed with water, dried (MgSO4) and evaporated under reduced pressure. Purification was by chromatography eluting with 40-50% ethyl acetate in isohexane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06218376B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-f10df7e12b0b47ecb0ea620d43f44c2e |
| 출처 메모 | uspto-grants-2001_04 |