Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4'-Methoxyacetophenone → (S)-1-(4-Methoxyphenyl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4'-Methoxyacetophenone | HCID 7476 | — |
| 반응물 | 1-(4-Methoxyphenyl)ethanol | HCID 101148 | — |
| 반응물 | (1R)-1-(4-methoxyphenyl)ethan-1-ol | HCID 641443 | — |
| 생성물 | (S)-1-(4-Methoxyphenyl)ethanol | HCID 6950190 | 48% |
반응 단계
As shown here, the biochemical conversion reaction of immobilized green pea protein for the substrate (±)-1-(4-methoxyphenyl)ethanol (200 mg) requires 7 days by going through bioconversion to 4-methoxyacetophenone accompanying sterically selective oxidation of (R)-1-(4-methoxyphenyl)ethanol to obtain 96 mg of (S)-1-(4-methoxyphenyl)ethanol at a yield of 48%. Optical purity was obtained at 95% e.e. Furthermore, HPLC conditions were set at a flow rate of 1.0 ml/min, while GC conditions were set to an oven temperature of 190° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06218581B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-f42b498c7bc14a1281df39bc764373c6 |
| 출처 메모 | uspto-grants-2001_04 |