Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Dimethylpropargylamine → 2-{2-[3-(Dimethylamino)prop-1-yn-1-yl]-1-methyl-4-phenyl-1H-imidazol-5-yl}[1,3]thiazolo[5,4-d]pyrimidin-7-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Dimethylpropargylamine | HCID 81643 | — |
| 반응물 | 2-{1-Methyl-4-phenyl-2-[(trimethylsilyl)ethynyl]-1H-imidazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine | HCID 69194173 | — |
| 생성물 | 2-{2-[3-(Dimethylamino)prop-1-yn-1-yl]-1-methyl-4-phenyl-1H-imidazol-5-yl}[1,3]thiazolo[5,4-d]pyrimidin-7-amine | HCID 69196904 | — |
반응 단계
The title compound was prepared by a similar process to that described for Intermediate 45 but using 1-dimethylamino-2-propyne in place of trimethylsilyl acetylene. Colourless solid (25 mg, 64%);
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07427616B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-d8b8b1dd6abf448eb7b3801d6269f3ed |
| 출처 메모 | uspto-grants-2008_09 |