Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 3-(1-Acetyl-4-piperidinyl)propionyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 3-(1-Acetylpiperidin-4-yl)propanoic acid | HCID 9855751 | — |
| 생성물 | 3-(1-Acetyl-4-piperidinyl)propionyl chloride | HCID 10465951 | — |
반응 단계
To 100 ml of thionyl chloride was added 26 g of 3-(1-acetylpiperidin-4-yl)propionic acid, obtained in Reference Example 1-(2), in small portions with ice-cooling. The mixture was stirred for 5 minutes, after which the excess thionyl chloride was distilled off and the solid residue was washed with diethyl ether to give 26.4 g of 3-(1-acetylpiperidin-4-yl)propionyl chloride as a pale yellow powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05273974 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-d878f7c71dea4699bd97b412d55dc53e |
| 출처 메모 | uspto-grants-1993_12 |