Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Propanediol → HCID 178520883, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Propanediol | HCID 10442 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | HCID 178478565 | HCID 178478565 | — |
| 생성물 | HCID 178520883 | HCID 178520883 | — |
반응 단계
Sodium (13.5 g.) was added over 3 hours to propane-1,3-diol (450 ml.) under nitrogen at 70° with stirring. This solution was added over 20 minutes to a stirred solution of 4-chloromethylimidazole hydrochloride (50.0 g.) under nitrogen at 40°-60°. Subsequent heating at 60°-65° for 3 hours followed by overnight cooling, filtration and concentration gave 4-(3-hydroxypropoxy)methylimidazole. Subsequent reaction with thionyl chloride gave 4-(3-chloropropoxy)methylimidazole hydrochloride (38.8 g.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04018931 |
| 출처 데이터셋 | uspto-grants-1977_04 |
| ORD ID | ord-5c1ba8c436c741fabf3f82616f0952a1 |
| 출처 메모 | uspto-grants-1977_04 |