Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → Ethyl 2-methylacetoacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Ethyl benzoylacetate | HCID 7170 | — |
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | Ethyl 2-oxocyclopentanecarboxylate | HCID 69136 | — |
| 반응물 | Ethyl 2-methyl-beta-oxobenzenepropanoate | HCID 2760276 | — |
| 생성물 | Ethyl 2-methylacetoacetate | HCID 701 | — |
| 생성물 | Ethyl 1-methyl-2-oxocyclopentane-1-carboxylate | HCID 227353 | — |
| 생성물 | Ethyl 2,2-dimethylbenzoylacetate | HCID 68118422 | — |
반응 단계
When the thallous salts of ethyl acetoacetate, 2-carbethoxycyclopentanone, ethyl benzoylacetate, and ethyl 2-methylbenzoylacetate, prepared according to Example 1, are refluxed with methyl iodide as described in Example 1 for periods of about 4, 9, 4, and 14 hours, respectively, ethyl 2-methylacetoacetate (b.p. 82°/25 mm.), 2-methyl-2-carbethoxycyclopentanone (b.p. 124°-126°/35 mm.), ethyl 2-methylbenzoyl acetate (b.p. 96°-97°/0.25 mm.), ), and ethyl 2,2-dimethylbenzoylacetate (b.p. 98°-100°/0.35 mm.), respectively, are obtained in quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04020073 |
| 출처 데이터셋 | uspto-grants-1977_04 |
| ORD ID | ord-8ebda59bd5414c03b8ae05616bd75bb4 |
| 출처 메모 | uspto-grants-1977_04 |