Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride → 4-Chloro-3-hydroxybutyric acid ethyl ester, (3R)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride | HCID 3080792 | — |
| 반응물 | Butanoic acid, 4-chloro-3-hydroxy-, ethyl ester | HCID 4377704 | — |
| 생성물 | 4-Chloro-3-hydroxybutyric acid ethyl ester, (3R)- | HCID 2734445 | — |
반응 단계
The resulting product was esterified with (R)α-methoxy-α-trifluoromethylphenylacetyl chloride, and the ester was analyzed by HPLC. From the area ratio of the chromatogram, the optical yield of the product was found to be 97.2% ee.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04895979 |
| 출처 데이터셋 | uspto-grants-1990_01 |
| ORD ID | ord-e77df226a15942e0a532ac81d947a918 |
| 출처 메모 | uspto-grants-1990_01 |