Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Chloro-2-(piperazin-1-yl)-1,3-benzothiazole → [4-(6-Chloro-benzothiazol-2-yl)-piperazin-1-yl]-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Chloro-2-(piperazin-1-yl)-1,3-benzothiazole | HCID 2746595 | — |
| 반응물 | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| 생성물 | [4-(6-Chloro-benzothiazol-2-yl)-piperazin-1-yl]-(2-isopropoxy-5-methanesulfonyl-phenyl)-methanone | HCID 11648903 | — |
반응 단계
Prepared in analogy to example 1.1 b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.2) and 6-chloro-2-piperazin-1-yl-benzothiazole. The crude material was purified by chromatography (SiO2, CH2Cl2/MeOH=95/5) to yield the title compound as a yellowish solid. MS (m/e): 552.3 (M+CH3COOH+)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429585B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-5268c11bda30498b84116ce689da3065 |
| 출처 메모 | uspto-grants-2008_09 |