Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromoquinoline → 4-Quinolin-3-yl-piperazine-1-carboxylic acid tert.-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromoquinoline | HCID 21413 | — |
| 반응물 | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| 생성물 | 4-Quinolin-3-yl-piperazine-1-carboxylic acid tert.-butyl ester | HCID 58906302 | — |
반응 단계
Prepared in analogy to example 1.16(a) from 3-bromoquinoline and piperazine-1-carboxylic acid tert-butyl ester. Chromatography (SiO2; cyclohexane/ethyl acetate 1/1), followed by crystallization from diethyl ether/cyclohexane yields the title product as a colorless solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429585B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-4db928d3fbef450ba6490b6ca93b490b |
| 출처 메모 | uspto-grants-2008_09 |