참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Isobutanol | HCID 6560 | — |
| 반응물 | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| 반응물 | 2,2-Dimethoxypropanal | HCID 7568181 | — |
| 생성물 | 1,1-Dimethoxy-4-dimethylaminobut-3-en-2-one | HCID 5709580 | 48% |
반응 단계
A mixture of N,N-dimethylformamide dimethylacetal (86.0 g, 584 mmol) and methylglyoxal 1,1-dimethylacetal (85.6 g, 724 mmol) in isobutanol (500 mL) was heated at 100° C. overnight. The mixture was then cooled and evaporated. Purification by distillation afforded the title product (49.9 g, 48%) as an orange liquid. Bp 123-124° C. at 0.9 mbar. MS: m/e=174.4 [M+H]′.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08877782B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_11 |
|---|
| ORD ID | ord-b5db251d32ce4ad086d5d5a696c41297 |
|---|
| 출처 메모 | uspto-grants-2014_11 |
|---|
