Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Nitrophenyl)-morpholin-3-ON → 4-(4-Aminophenyl)morpholin-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Nitrophenyl)-morpholin-3-ON | HCID 11447375 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 4-(4-Aminophenyl)morpholin-3-one | HCID 11194854 | — |
반응 단계
To a solution of 2.6 g 4-(4-Nitro-phenyl)-morpholin-3-one in 350 ml ethyl acetate and 17 ml ethanol, 13.2 g SnCl2 dihydrate were added and the reaction mixture was heated to reflux for 2 h. Then after cooling to RT the mixture was stirred for 16 h. The precipitated product was collected by filtration and was pure enough for the next reaction step. Yield: 2.07 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07429581B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-2d9233f596b449578394ee61ada102cf |
| 출처 메모 | uspto-grants-2008_09 |